| Insider Name | Buy/Sell | Amount | Shares Change | |||
|---|---|---|---|---|---|---|
| Mar 26, 2018 | Mar 28, 2018 | Wolf Dennis P Dir | Sell | $11.15 | $464,384 | -26.38% |
| Mar 22, 2018 | Mar 24, 2018 | Nicols John J Pres CEO | Sell | $11.57 | $259,828 | -2.05% |
| Mar 21, 2018 | Mar 22, 2018 | Kelley Bernard J Dir | Sell | $12.22 | $124,683 | -4.25% |
| Aug 21, 2015 | Dec 08, 2017 | Yang Patrick Y Dir | Buy | $3.98 | $39,769 | +2.79% |
| Sep 14, 2017 | Sep 19, 2017 | Vivo Ventures Fund Vii, L.P. 10% | Sell | $5.78 | $6M | -20.02% |
| Nov 15, 2016 | Nov 16, 2016 | Yang Patrick Y Dir | Buy | $4.83 | $48,300 | +3.03% |
| Sep 08, 2016 | Sep 12, 2016 | Vivo Ventures Vii, LLC 10% | Sell | $4.25 | $474,624 | -2.06% |
| Aug 26, 2016 | Aug 31, 2016 | Wolf Dennis P Dir | Sell | $4.22 | $75,974 | -12.73% |
| Aug 24, 2016 | Aug 27, 2016 | Kelley Bernard J Dir | Sell | $4.26 | $53,807 | -5.38% |
| Aug 15, 2016 | Aug 17, 2016 | Vivo Ventures Vii, LLC 10% | Sell | $4.25 | $368,920 | -1.58% |
| Aug 03, 2016 | Aug 06, 2016 | Vivo Ventures Vii, LLC 10% | Sell | $4.22 | $337,369 | -1.44% |
| Nov 10, 2015 | Nov 12, 2015 | Lalonde James SVP R D | Sell | $3.52 | $33,234 | -5.32% |
| Sep 11, 2015 | Sep 15, 2015 | Yang Patrick Y Dir | Buy | $3.47 | $34,711 | +3.33% |
| Sep 10, 2015 | Sep 11, 2015 | Kelley Bernard J Dir | Sell | $3.45 | $17,964 | -2.62% |
| Aug 24, 2015 | Aug 25, 2015 | Yang Patrick Y Dir | Buy | $3.84 | $38,353 | +3.45% |
| Aug 14, 2015 | Aug 17, 2015 | Yang Patrick Y Dir | Buy | $3.97 | $79,484 | +6.89% |
| Jun 12, 2015 | Jun 16, 2015 | Wolf Dennis P Dir | Sell | $4.1 | $145,262 | -22.60% |
| Nov 18, 2014 | Nov 20, 2014 | Yang Patrick Y Dir | Buy | $2.35 | $47,000 | +8.02% |
| Nov 17, 2014 | Nov 19, 2014 | Yang Patrick Y Dir | Buy | $2.34 | $46,800 | +8.71% |
| Nov 10, 2014 | Nov 12, 2014 | Cmea Ventures Life Sciences 2000 LP Dir 10% | Sell | $2.37 | $7M | -0 |
| Aug 12, 2014 | Aug 15, 2014 | Yang Patrick Y Dir | Buy | $2.22 | $133,200 | +24.05% |