| Insider Name | Buy/Sell | Amount | Shares Change | |||
|---|---|---|---|---|---|---|
| Jan 08, 2016 | Jan 12, 2016 | Schafer Gregory W COO | Sell | $23.58 | $471,600 | -28.87% |
| Jan 04, 2016 | Jan 06, 2016 | Dubensky Thomas W. Chief Scientific Officer | Sell | $26.37 | $395,531 | -0 |
| Jan 04, 2016 | Jan 06, 2016 | Isaacs Stephen T Pres CEO | Sell | $26.31 | $657,799 | -13.08% |
| Jan 06, 2016 | Jan 06, 2016 | Lew Jennifer SVP of Finance | Sell | $25.71 | $134,765 | -45.81% |
| Dec 10, 2015 | Dec 14, 2015 | Brockstedt Dirk G. SVP of Research Dev. | Sell | $29.82 | $745,423 | -0 |
| Dec 07, 2015 | Dec 08, 2015 | Schafer Gregory W COO | Sell | $29.74 | $743,571 | -42.17% |
| Dec 03, 2015 | Dec 08, 2015 | Lew Jennifer SVP of Finance | Sell | $29.85 | $156,486 | -72.38% |
| Dec 01, 2015 | Dec 02, 2015 | Isaacs Stephen T Pres CEO | Sell | $29.11 | $727,664 | -13.80% |
| Dec 01, 2015 | Dec 02, 2015 | Dubensky Thomas W. Chief Scientific Officer | Sell | $29.27 | $878,104 | -0 |
| Nov 30, 2015 | Dec 02, 2015 | Greenman William Mariner Dir | Sell | $30.65 | $91,950 | -0 |
| Nov 18, 2015 | Nov 19, 2015 | Lew Jennifer SVP of Finance | Sell | $28.52 | $191,426 | -77.04% |
| Nov 16, 2015 | Nov 19, 2015 | Isaacs Stephen T Pres CEO | Sell | $27.54 | $688,490 | -13.80% |
| Nov 16, 2015 | Nov 19, 2015 | Brockstedt Dirk G. SVP of Research Dev. | Sell | $28.34 | $750,028 | -0 |
| Nov 16, 2015 | Nov 19, 2015 | Schafer Gregory W COO | Sell | $28.15 | $745,241 | -43.57% |
| Nov 16, 2015 | Nov 19, 2015 | Dubensky Thomas W. Chief Scientific Officer | Sell | $28.27 | $889,556 | -0 |
| Apr 20, 2015 | Apr 22, 2015 | Rogers John E. and Lois A. 10% | Buy | $17 | $297,500 | +10.56% |
| Apr 20, 2015 | Apr 22, 2015 | Rogers John E. and Lois A. 10% | Buy | $17 | $2M | +2.34% |
| Apr 20, 2015 | Apr 22, 2015 | Morningside Venture (Vi) Investments Ltd 10% | Buy | $17 | $7M | +2.26% |
| Apr 20, 2015 | Apr 22, 2015 | Obrien Stephanie Monaghan Dir | Buy | $17 | $57,800 | +50.00% |
| Apr 20, 2015 | Apr 22, 2015 | Greenman William Mariner Dir | Buy | $17 | $51,000 | +50.00% |
| Apr 20, 2015 | Apr 22, 2015 | Lew Jennifer SVP of Finance | Buy | $17 | $34,000 | +50.00% |