| Insider Name | Buy/Sell | Amount | Shares Change | |||
|---|---|---|---|---|---|---|
| Apr 05, 2022 | Apr 07, 2022 | Turner William D. Chief Reg Tech Ops Officer | Sell | $37.25 | $240,118 | -0 |
| Apr 04, 2022 | Apr 04, 2022 | Thomson Mary Christina GC CCO Sec'y | Sell | $35.14 | $70,277 | -0 |
| Mar 18, 2022 | Mar 22, 2022 | Turner William D. Chief Reg Tech Ops Officer | Sell | $37.05 | $3,705 | -0 |
| Mar 17, 2022 | Mar 17, 2022 | Turner William D. Chief Reg Tech Ops Officer | Sell | $37.06 | $127,954 | -0 |
| Mar 04, 2022 | Mar 04, 2022 | Thomson Mary Christina GC CCO Sec'y | Sell | $30.6 | $61,196 | -0 |
| Feb 07, 2022 | Feb 08, 2022 | Turner William D. Chief Reg Tech Ops Officer | Sell | $32.32 | $323,225 | -0 |
| Feb 04, 2022 | Feb 04, 2022 | Thomson Mary Christina GC CCO Sec'y | Sell | $29.78 | $59,560 | -0 |
| Feb 02, 2022 | Feb 03, 2022 | Longitude Capital Partners Iii, LLC 10% | Buy | $27 | $5M | +7.56% |
| Feb 02, 2022 | Feb 03, 2022 | Richardson Joshua Dir 10% | Buy | $27 | $5M | +7.56% |
| Jan 31, 2022 | Feb 01, 2022 | Sinclair Andrew Dir | Buy | $27 | $4M | +10.25% |
| Jan 31, 2022 | Feb 01, 2022 | Abingworth LLP 10% | Buy | $27 | $4M | +10.25% |
| Jan 31, 2022 | Feb 01, 2022 | Vivo Opportunity, LLC 10% | Buy | $27 | $22M | +19.37% |
| Jan 31, 2022 | Jan 31, 2022 | Aggarwal Gaurav Dir 10% | Buy | $27 | $22M | +22.63% |
| Jan 26, 2022 | Jan 28, 2022 | Thomson Mary Christina GC Secretary | Sell | $29 | $58,000 | -0 |
| Jan 26, 2022 | Jan 28, 2022 | Turner William D. Chief Reg Tech Ops Officer | Sell | $27.05 | $135,250 | -0 |
| Nov 23, 2021 | Nov 25, 2021 | Collard Craig A Dir | Buy | $23.03 | $310,863 | +50.00% |
| May 19, 2021 | May 20, 2021 | Dilly Stephen George CEO Pres | Buy | $17.83 | $89,150 | +50.00% |
| Aug 18, 2020 | Aug 19, 2020 | Klencke Barbara Chief Development Officer | Buy | $12.23 | $113,447 | +38.21% |
| Aug 22, 2019 | Aug 26, 2019 | Klencke Barbara Chief Development Officer | Buy | $0.44 | $100,638 | +50.00% |
| Dec 10, 2018 | Dec 11, 2018 | Allen Andrew R Dir | Buy | $1.64 | $108,240 | +50.00% |
| Mar 08, 2017 | Mar 09, 2017 | You Angie Chief Bus. Strat. Officer | Buy | $1.43 | $42,900 | +18.38% |
| Feb 14, 2017 | Feb 16, 2017 | Topper James N Dir 10% | Buy | $1.35 | $8M | +42.21% |