| Insider Name | Buy/Sell | Amount | Shares Change | |||
|---|---|---|---|---|---|---|
| Jan 10, 2018 | Jan 12, 2018 | Kanes Stephen Chief Medical Officer | Sell | $177.18 | $8M | -65.72% |
| Dec 21, 2017 | Dec 22, 2017 | Jonas Jeffrey M Pres CEO | Sell | $157.31 | $35M | -99.45% |
| Dec 14, 2017 | Dec 14, 2017 | Robichaud Albert Chief Scientific Officer | Sell | $159.43 | $10M | -38.90% |
| Jan 13, 2017 | Jan 13, 2017 | Iguchi Kimi CFO Secretary Treasurer | Sell | $53.92 | $539,200 | -13.07% |
| Nov 15, 2016 | Nov 28, 2016 | Anderson Thomas | Sell | $55 | $550,000 | -0 |
| Nov 17, 2016 | Nov 18, 2016 | Iguchi Kimi CFO Secretary Treasurer | Sell | $51.77 | $207,080 | -5.02% |
| Nov 11, 2016 | Nov 14, 2016 | Iguchi Kimi CFO Secretary Treasurer | Sell | $50.59 | $75,885 | -1.85% |
| Sep 07, 2016 | Sep 09, 2016 | Iguchi Kimi CFO Secretary Treasurer | Sell | $40.93 | $102,325 | -2.99% |
| Jul 12, 2016 | Jul 14, 2016 | Robichaud Albert Chief Scientific Officer | Sell | $40 | $880,000 | -13.56% |
| Jul 12, 2016 | Jul 14, 2016 | Iguchi Kimi CFO Secretary Treasurer | Sell | $49.55 | $247,750 | -5.63% |
| May 16, 2016 | May 18, 2016 | Third Rock Ventures Ii, L.P. 10% | Sell | $31.25 | $27M | -17.44% |
| May 16, 2016 | May 18, 2016 | Starr Kevin P Dir 10% | Sell | $31.25 | $27M | -17.68% |
| Apr 19, 2016 | Apr 21, 2016 | Kanes Stephen Chief Medical Officer | Sell | $38 | $798,000 | -30.91% |
| Jan 25, 2016 | Jan 26, 2016 | Robichaud Albert Chief Scientific Officer | Sell | $40.02 | $800,400 | -10.98% |
| Dec 31, 2015 | Jan 07, 2016 | Iguchi Kimi CFO Secretary Treasurer | Buy | $49.56 | $8,723 | +0.20% |
| Dec 31, 2015 | Jan 07, 2016 | Jonas Jeffrey M | Buy | $49.56 | $11,201 | +0.22% |
| Sep 28, 2015 | Sep 29, 2015 | Kanes Stephen Chief Medical Officer | Sell | $46.42 | $278,520 | -11.33% |
| Sep 08, 2015 | Sep 09, 2015 | Iguchi Kimi CFO Secretary Treasurer | Sell | $54.84 | $164,520 | -3.43% |
| Sep 01, 2015 | Sep 02, 2015 | Paul Steven M Dir | Sell | $52.41 | $1M | -2.84% |
| Aug 31, 2015 | Sep 01, 2015 | Kanes Stephen Chief Medical Officer | Sell | $53.12 | $637,440 | -27.30% |
| Aug 10, 2015 | Aug 11, 2015 | Anderson Thomas | Sell | $67.05 | $402,310 | -0 |
| Aug 10, 2015 | Aug 11, 2015 | Iguchi Kimi CFO Secretary Treasurer | Sell | $67.61 | $270,425 | -4.37% |
| Aug 03, 2015 | Aug 04, 2015 | Robichaud Albert Chief Scientific Officer | Sell | $67.06 | $804,720 | -6.18% |
| Aug 03, 2015 | Aug 04, 2015 | Paul Steven M Dir | Sell | $67.08 | $1M | -2.76% |
| Jul 27, 2015 | Jul 29, 2015 | Kanes Stephen Chief Medical Officer | Sell | $70.24 | $346,723 | -10.10% |
| Jul 23, 2015 | Jul 24, 2015 | Jonas Jeffrey M | Sell | $76.79 | $230,370 | -3.57% |
| Jul 06, 2015 | Jul 06, 2015 | Iguchi Kimi CFO Secretary Treasurer | Sell | $68 | $272,000 | -4.19% |
| Jul 01, 2015 | Jul 02, 2015 | Paul Steven M Dir | Sell | $69.4 | $1M | -2.69% |
| Jul 01, 2015 | Jul 01, 2015 | Robichaud Albert Chief Scientific Officer | Sell | $72.13 | $1M | -7.61% |
| Jun 24, 2015 | Jun 25, 2015 | Kanes Stephen Chief Medical Officer | Sell | $74.06 | $444,360 | -11.33% |