| Insider Name | Buy/Sell | Amount | Shares Change | |||
|---|---|---|---|---|---|---|
| Apr 24, 2018 | Apr 26, 2018 | Burstein Jennifer SVP of Finance | Sell | $131.65 | $223,805 | -0 |
| Apr 24, 2018 | Apr 26, 2018 | Van Naarden Jacob Chief Business Officer | Sell | $131.23 | $404,461 | -0 |
| Apr 24, 2018 | Apr 26, 2018 | Bilenker Joshua H. Pres CEO | Sell | $131.12 | $2M | -7.59% |
| Apr 20, 2018 | Apr 24, 2018 | Kunkel Lori Anne Dir | Sell | $132.68 | $663,378 | -42.23% |
| Mar 13, 2018 | Mar 15, 2018 | Burstein Jennifer SVP of Finance | Sell | $131.33 | $223,262 | -0 |
| Mar 13, 2018 | Mar 15, 2018 | Van Naarden Jacob Chief Business Officer | Sell | $131.41 | $404,995 | -0 |
| Mar 13, 2018 | Mar 15, 2018 | Bilenker Joshua H. Pres CEO | Sell | $131.54 | $2M | -7.59% |
| Feb 12, 2018 | Feb 14, 2018 | Burstein Jennifer SVP of Finance | Sell | $93.24 | $158,504 | -0 |
| Feb 12, 2018 | Feb 14, 2018 | Bilenker Joshua H. Pres CEO | Sell | $96.57 | $1M | -7.59% |
| Feb 12, 2018 | Feb 14, 2018 | Van Naarden Jacob Chief Business Officer | Sell | $96.34 | $296,912 | -0 |
| Jan 22, 2018 | Jan 25, 2018 | Naider Avi Z. Dir | Sell | $100 | $2M | -10.63% |
| Jan 16, 2018 | Jan 18, 2018 | Burstein Jennifer SVP of Finance | Sell | $87.5 | $131,243 | -0 |
| Jan 16, 2018 | Jan 18, 2018 | Van Naarden Jacob Chief Business Officer | Sell | $88.21 | $271,866 | -0 |
| Jan 16, 2018 | Jan 18, 2018 | Bilenker Joshua H. Pres CEO | Sell | $88.21 | $1M | -7.59% |
| Dec 20, 2017 | Dec 22, 2017 | Mayleben Timothy M Dir | Sell | $80.49 | $804,948 | -0 |
| Dec 19, 2017 | Dec 20, 2017 | Aisling Capital III LP 10% | Sell | $80.5 | $20M | -6.78% |
| Dec 14, 2017 | Dec 18, 2017 | Burstein Jennifer VP of Finance | Sell | $83.27 | $141,554 | -0 |
| Dec 14, 2017 | Dec 18, 2017 | Van Naarden Jacob Chief Business Officer | Sell | $81.19 | $250,240 | -0 |
| Dec 14, 2017 | Dec 18, 2017 | Bilenker Joshua H. Pres CEO | Sell | $81.12 | $1M | -7.59% |
| Dec 08, 2017 | Dec 12, 2017 | Bonita David P Dir | Sell | $82.5 | $21M | -20.99% |
| Dec 08, 2017 | Dec 12, 2017 | Orbimed Advisors LLC Dir | Sell | $82.5 | $21M | -20.99% |
| Nov 27, 2017 | Nov 29, 2017 | Burstein Jennifer VP of Finance | Sell | $74.82 | $127,193 | -0 |
| Nov 27, 2017 | Nov 29, 2017 | Van Naarden Jacob Chief Business Officer | Sell | $74.5 | $229,598 | -0 |
| Nov 27, 2017 | Nov 29, 2017 | Bilenker Joshua H. Pres CEO | Sell | $74.45 | $1M | -7.59% |
| Nov 22, 2017 | Nov 28, 2017 | Aisling Capital III LP 10% | Sell | $75 | $38M | -11.94% |
| Nov 22, 2017 | Nov 27, 2017 | Mayleben Timothy M Dir | Sell | $75.85 | $227,563 | -23.08% |
| Nov 22, 2017 | Nov 27, 2017 | Bonita David P Dir | Sell | $75 | $20M | -18.31% |
| Nov 22, 2017 | Nov 27, 2017 | Orbimed Advisors LLC Dir | Sell | $75 | $20M | -18.31% |
| Nov 20, 2017 | Nov 22, 2017 | Flaherty Keith T. Dir | Sell | $75.99 | $550,921 | -42.69% |
| Nov 16, 2017 | Nov 21, 2017 | Bonita David P Dir | Sell | $74.26 | $20M | -15.63% |