| Insider Name | Buy/Sell | Amount | Shares Change | |||
|---|---|---|---|---|---|---|
| Jul 31, 2018 | Aug 02, 2018 | Roche Holdings Inc See footnote (1) 10% | Buy | $137 | $2B | +30.34% |
| Jul 02, 2018 | Jul 05, 2018 | Ryan Jason CFO | Sell | $136.66 | $465,054 | -6.47% |
| Jul 02, 2018 | Jul 05, 2018 | Nallicheri Melanie Chief Business Officer | Sell | $136.66 | $274,413 | -2.95% |
| Jul 02, 2018 | Jul 05, 2018 | Miller Vincent A. Chief Medical Officer | Sell | $136.66 | $397,544 | -4.15% |
| Jul 02, 2018 | Jul 05, 2018 | Hesslein Robert W. SVP GC | Sell | $136.66 | $344,383 | -2.34% |
| Jul 02, 2018 | Jul 05, 2018 | Fiedler Konstantin COO | Sell | $136.66 | $135,840 | -3.57% |
| Jul 02, 2018 | Jul 05, 2018 | Doherty Michael J Head of Product Development | Sell | $136.66 | $365,566 | -3.19% |
| Jul 02, 2018 | Jul 05, 2018 | Cox Troy CEO | Sell | $136.66 | $191,597 | -0.58% |
| Jun 15, 2018 | Jun 19, 2018 | Pellini Michael J Dir | Sell | $105.45 | $369,075 | -3.26% |
| May 21, 2018 | May 23, 2018 | Miller Vincent A. Chief Medical Officer | Sell | $85 | $133,450 | -2.19% |
| May 16, 2018 | May 17, 2018 | Cox Troy CEO | Sell | $77.1 | $166,305 | -0.88% |
| May 15, 2018 | May 17, 2018 | Pellini Michael J Dir | Sell | $76.05 | $266,175 | -3.16% |
| May 07, 2018 | May 09, 2018 | Cox Troy CEO | Sell | $70.01 | $494,481 | -2.80% |
| Apr 16, 2018 | Apr 18, 2018 | Ryan Jason CFO | Sell | $74.3 | $256,261 | -6.16% |
| Apr 16, 2018 | Apr 18, 2018 | Pellini Michael J Dir | Sell | $74.65 | $261,275 | -3.06% |
| Apr 16, 2018 | Apr 18, 2018 | Miller Vincent A. Chief Medical Officer | Sell | $74.02 | $243,008 | -4.47% |
| Apr 03, 2018 | Apr 05, 2018 | Ryan Jason CFO | Sell | $72.4 | $72 | -0.00% |
| Apr 03, 2018 | Apr 05, 2018 | Doherty Michael J Head of Product Development | Sell | $72.4 | $145 | -0.00% |
| Apr 03, 2018 | Apr 05, 2018 | Pellini Michael J Dir | Sell | $70.28 | $959,955 | -10.68% |
| Apr 02, 2018 | Apr 03, 2018 | Ryan Jason CFO | Sell | $76.23 | $467,959 | -9.88% |
| Apr 02, 2018 | Apr 03, 2018 | Nallicheri Melanie Chief Business Officer | Sell | $74.88 | $93,825 | -1.81% |
| Mar 09, 2018 | Apr 03, 2018 | Miller Vincent A. Chief Medical Officer | Sell | $85 | $1M | -20.98% |
| Apr 02, 2018 | Apr 03, 2018 | Miller Vincent A. Chief Medical Officer | Sell | $74.88 | $215,871 | -3.78% |
| Apr 02, 2018 | Apr 03, 2018 | Hesslein Robert W. SVP GC | Sell | $74.88 | $118,685 | -1.45% |
| Apr 02, 2018 | Apr 03, 2018 | Fiedler Konstantin COO | Sell | $74.88 | $26,807 | -1.27% |
| Apr 02, 2018 | Apr 03, 2018 | Doherty Michael J Head of Product Development | Sell | $74.87 | $613,185 | -8.89% |
| Mar 15, 2018 | Mar 19, 2018 | Pellini Michael J Dir | Sell | $78.29 | $274,015 | -2.66% |
| Mar 15, 2018 | Mar 19, 2018 | Ryan Jason CFO | Sell | $78.26 | $1M | -23.35% |
| Feb 20, 2018 | Mar 12, 2018 | Miller Vincent A. Chief Medical Officer | Sell | $85 | $1M | -20.98% |
| Feb 20, 2018 | Feb 22, 2018 | Miller Vincent A. Chief Medical Officer | Sell | $76.87 | $2M | -30.39% |