| Insider Name | Buy/Sell | Amount | Shares Change | |||
|---|---|---|---|---|---|---|
| Nov 27, 2018 | Nov 28, 2018 | Gurnet Holding Co 10% | Buy | $12.5 | $458M | +100.00% |
| Oct 11, 2018 | Oct 15, 2018 | Perceptive Advisors LLC 10% | Sell | $12.52 | $45M | -57.14% |
| Aug 17, 2018 | Aug 18, 2018 | Sweemer Timothy D Chief Accounting Officer | Sell | $9.01 | $3,117 | -0.98% |
| Aug 17, 2018 | Aug 18, 2018 | Singh Parminder CTO VP R D | Sell | $9.01 | $28,224 | -16.49% |
| Aug 17, 2018 | Aug 18, 2018 | Sarret Joseph J. Chief Business Officer | Sell | $9.01 | $32,116 | -18.03% |
| Aug 17, 2018 | Aug 18, 2018 | Breuil Robert S CFO | Sell | $9.01 | $8,756 | -6.31% |
| Aug 16, 2018 | Aug 18, 2018 | Staple Peter D Pres CEO | Sell | $8.81 | $672,524 | -21.26% |
| Aug 15, 2018 | Aug 17, 2018 | Thomas Robert Dir | Sell | $8.86 | $315,476 | -0 |
| Jan 16, 2018 | Jan 18, 2018 | Perceptive Advisors LLC 10% | Buy | $12.54 | $6M | +7.43% |
| Nov 16, 2017 | Nov 17, 2017 | Broadfin Healthcare Master Fund Ltd 10% | Sell | $10.96 | $5M | -12.29% |
| Nov 02, 2017 | Nov 03, 2017 | Broadfin Healthcare Master Fund Ltd 10% | Sell | $11.05 | $2M | -3.56% |
| Oct 04, 2017 | Oct 06, 2017 | Broadfin Healthcare Master Fund Ltd 10% | Sell | $11.01 | $2M | -4.92% |
| Aug 21, 2017 | Aug 23, 2017 | Singh Parminder CTO VP R D | Sell | $7.59 | $230,700 | -79.30% |
| Aug 16, 2017 | Aug 18, 2017 | Sweemer Timothy D Chief Accounting Officer | Sell | $7.73 | $212,685 | -45.94% |
| Aug 17, 2017 | Aug 18, 2017 | Singh Parminder CTO VP R D | Sell | $7.61 | $243,619 | -45.48% |
| Jul 20, 2017 | Jul 22, 2017 | Sarret Joseph J. Chief Business Officer | Sell | $8.95 | $18,232 | -21.45% |
| Jun 30, 2017 | Jul 05, 2017 | Perceptive Advisors LLC 10% | Buy | $7.71 | $2M | +4.90% |
| May 25, 2017 | May 25, 2017 | Perceptive Advisors LLC 10% | Buy | $6.25 | $12M | +25.54% |
| May 18, 2016 | May 20, 2016 | Bjerkholt Eric Dir | Buy | $3.64 | $89,200 | +50.00% |
| May 12, 2016 | May 16, 2016 | Greenwood David Dir | Buy | $3.58 | $10,742 | +50.00% |
| Feb 25, 2015 | Feb 26, 2015 | Staple Peter D Pres CEO | Buy | $6.99 | $25,169 | +13.34% |
| Nov 21, 2014 | Nov 25, 2014 | Staple Peter D Pres CEO | Buy | $5.34 | $48,055 | +31.27% |
| Nov 21, 2014 | Nov 25, 2014 | Breuil Robert S CFO | Buy | $5.38 | $24,759 | +45.10% |
| Aug 25, 2014 | Aug 27, 2014 | Staple Peter D Pres CEO | Buy | $6.1 | $15,729 | +20.86% |
| May 28, 2014 | May 30, 2014 | Staple Peter D Pres CEO | Buy | $7.04 | $50,706 | +50.00% |
| Apr 08, 2014 | Apr 08, 2014 | Essex Woodlands Health Ventures Fund VII LP 10% | Buy | $8 | $3M | +4.10% |
| Apr 08, 2014 | Apr 08, 2014 | Eastman Ronald W Dir 10% | Buy | $8 | $3M | +4.10% |
| Apr 08, 2014 | Apr 08, 2014 | Cleary Gary W Dir | Sell | ~ | $0 | -63.12% |